磷酸酯酶3蛋白抗体
规格：1mg/1ml
英文名： PRL3
别名： PRL-R;Potentially prenylated protein tyrosine phosphatase; PRL 3; PRL R; PRLR: PRL3; PRLR; Protein tyrosine phosphatase 4a3; PTP 4A3: PTP4A3.
分子量： 19kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PRL3/PTP
交叉反应：Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, Sheep, Guinea Pig, Danio
细胞定位：细胞浆 细胞膜
磷酸酯酶3蛋白抗体产品介绍：background: PTP4A3 protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. It enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. It may be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II. PTP4A3 interacts with tubulin. It belongs to the protein tyrosine phosphatase family. It is mainly expressed in cardiomyocytes and skeletal muscle; also found in磷酸酯酶3蛋白抗体 pancreas. It is consistently overexpressed in colon cancer metastasis. Subunit: Interacts with tubulin. Subcellular Location: Cell membrane. Early endosome. Tissue Specificity: Mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. Consistently overexpressed in colon cancer metastasis. Similarity: Belongs to the protein-tyrosine phosphatase family. Contains 1 tyrosine-protein phosphatase 磷酸酯酶3蛋白抗体domain. Gene ID: 11156 Database links: Entrez Gene: 11156 Human Entrez Gene: 19245 Mouse Entrez Gene: 362930 Rat Entrez Gene: 406460 Zebrafish Omim: 606449 Human SwissProt: O75365 Human SwissProt: Q9D658 Mouse SwissProt: Q78EG7 Rat SwissProt: Q6NX92 Zebrafish Unigene: 43666 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸酯酶3蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 信号转导 转录调节因子 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid