驱动蛋白家族KIF17抗体
规格：1mg/1ml
英文名： KIF17
别名： KIAA1405; KIF 17; KIF 17B; KIF 3X; KIF17B; KIF3-related motor protein; KIF3X; Kinesin family member 17; Kinesin like protein KIF 17; Kinesin like protein KIF17; KIF17_HUMAN.
分子量： 115kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KIF17
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位：细胞浆
驱动蛋白家族KIF17抗体产品介绍：background: The kinesin superfamily of proteins (KIFs) consists of a class of microtubule-dependent motors that play a major role in many cellular and developmental functions, including organelle transport, mitosis, meiosis, and possibly long-range signaling in neurons. The kinesin proteins are involved in organelle transport and are primarily associated with anterograde transport of vesicles and organelles in neurons, epithelial cells, and melanosomes with bidirectional transport of mitochondria. They also mediate transport between the endoplasmic reticulum (ER) and the Golgi complex. In neurons, kinesin motors conduct vesicular transport, such as of synaptic vesicle 驱动蛋白家族KIF17抗体components to axons and of neurotransmitter receptors to dendrites. KIF17 belongs to the functionally diverse subgroup of the kinesin superfamily characterized by a N-terminal motor domain (N-IV class), that includes the KIF3 motor protein. KIF17 is specifically expressed in the brain, present in abundance in the gray matter, particularly in the hippocampus and cerebral cortex, but not in the white matter such as the optic nerve. Function: Transports vesicles containing N-methyl-D-aspartate(NMDA) receptor 2B along microtubules (By similarity).驱动蛋白家族KIF17抗体 Subunit: Interacts with LIN-10 PDZ domain. Interacts with PIWIL1(By similarity). Interacts with TBATA (By similarity). Subcellular Location: Cytoplasm, cytoskeleton (Probable). Similarity: Belongs to the kinesin-like protein family. Contains 1 kinesin-motor domain. Gene ID: 57576 Database links: Entrez Gene: 57576 Human Entrez Gene: 16559 Mouse Omim: 605037 Human SwissProt: Q9P2E2 Human SwissProt: Q99PW8 Mouse Unigene: 130411 Human Unigene: 271936 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产驱动蛋白家族KIF17抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 神经生物学 信号转导 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid