磷酸化***腺衍生血管内皮生长因子抗体
规格:1mg/1ml
英文名: Phospho-PRK1 (Thr774) + PRK2 (Thr816) + PRK3 (Thr718)
别名: PRK3+PRK2+PRK1 (phospho T816 + T718 + T774); PROK1; Prokineticin-1/Endocrine-gland-derived vascular endothelial growth factor; EGVEGF; PK1; EG-VEGF; EG VEGF; PRK1; Prokineticin 1; Black mamba toxin re
分子量: 103kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthesised phosphopeptide derived from human
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位:细胞核 细胞浆 细胞膜
磷酸化***腺衍生血管内皮生长因子抗体产品介绍:background: The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner. [provided by RefSeq, Sep 2011] Function: Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation,磷酸化***腺衍生血管内皮生长因子抗体 but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis. Subcellular Location: Secreted. Tissue Specificity: Localizes to glandular epithelium, stroma and vascular epithelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the steroidogenic glands, ovary, testis, adrenal and placenta. Similarity: Belongs to the AVIT (prokineticin) 磷酸化***腺衍生血管内皮生长因子抗体family. Gene ID: 84432 Database links: Entrez Gene: 84432 Human Entrez Gene: 246691 Mouse Entrez Gene: 192205 Rat Omim: 606233 Human SwissProt: P58294 Human SwissProt: Q14A28 Mouse SwissProt: Q8R414 Rat Unigene: 514793 Human Unigene: 461353 Mouse Unigene: 82757 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. EG-VEGF是先被发现的组织特异性促血管生成因子,与多种特定组织肿瘤的发生及演进相关,EG-VEGF多在卵巢、睾丸、肾上腺、胎盘等类固醇合成组织中高表达。
磷酸化***腺衍生血管内皮生长因子抗体产品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 **学 血管内皮细胞
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid