磷酸化蛋白激酶GCN2蛋白抗体
规格:1mg/1ml
英文名: Phospho-GCN2 (Thr899)
别名: GCN2 (phospho T899); p-GCN2 (phospho T899); EIF2AK4; Eukaryotic Translation Initiation Factor 2-alpha kinase 4; GCN2-like protein; KIAA1338; E2AK4_HUMAN; Eif2ak4; Eukaryotic Translation Initiation Fac
分子量: 189kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated Synthesised phosphopeptide derived from human
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse,
细胞定位:
磷酸化蛋白激酶GCN2蛋白抗体产品介绍:background: GCN2 belongs to a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor 2 to downregulate protein synthesis in response to varied cellular stresses. Function: Can phosphorylate the alpha subunit of EIF2 and may mediate translational control. Tissue Specificity: Widely expressed. Post-translational modifications: Autophosphorylated on threonine residues. Similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. 磷酸化蛋白激酶GCN2蛋白抗体GCN2 subfamily. Contains 2 protein kinase domains. Contains 1 RWD domain. Gene ID: 440275 Database links: Entrez Gene: 440275 Human Entrez Gene: 27103 Mouse Entrez Gene: 114859 Rat Omim: 609280 Human SwissProt: Q9P2K8 Human SwissProt:磷酸化蛋白激酶GCN2蛋白抗体 Q9QZ05 Mouse Unigene: 656673 Human Unigene: 217616 Mouse Unigene: 8333 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. GCN2蛋白的作用;可能是将短期记忆变成长期记忆的一个主控调节因子, GCN2蛋白在长期记忆形成**能的发现将可能帮助研究人员开发出提高记忆力丧失的病人提高记忆力。
磷酸化蛋白激酶GCN2蛋白抗体产品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 染色质和核信号 神经生物学 信号转导 激酶和磷酸酶
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid