Ras相关结构域蛋白质2抗体
规格：1mg/1ml
英文名： RASSF2
别名： CENP 34; Centromere protein 34; Ras association (RalGDS/AF 6) domain family 2; Ras association (RalGDS/AF-6) domain family member 2; Ras association domain containing protein 2; Ras association domain
分子量： 38kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RASSF2
交叉反应：Human, Mouse, Rat, Dog, Pig, Horse,
细胞定位：
Ras相关结构域蛋白质2抗体产品介绍：background: Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Function: Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation. Subunit: Interacts directly with activated KRAS in a GTP-dependent manner. Interacts (via SARAH domain) with STK3/MST2 AND STK4/MST1. Subcellular Location: Nucleus. CytoplasmRas相关结构域蛋白质2抗体. Note=Translocates to the cytoplasm in the presence of STK3/MST2 AND STK4/MST1. Tissue Specificity: Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines. Post-translational modifications: Phosphorylated by STK3/MST2 and STK4/MST1. Similarity: Contains 1 Ras-associating domain. Contains 1 SARAH domain. Ras相关结构域蛋白质2抗体Database links: UniProtKB/Swiss-Prot: P50749.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Ras相关结构域蛋白质2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 染色质和核信号 信号转导 G蛋白偶联受体 表观遗传学 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid