溶血磷脂酸受体蛋白3/EDG7抗体
规格：1mg/1ml
英文名： LPA3
别名： Calcium mobilizing lysophosphatidic acid receptor LP A3; Calcium mobilizing lysophosphatidic acid receptor LPA 3; Calcium mobilizing lysophosphatidic acid receptor LPA3; EDG 7; Endothelial cell differ
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human EDG7/LPA
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：
溶血磷脂酸受体蛋白3/EDG7抗体产品介绍：background: EDG7 is a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins. EDG7 has been reported in human prostate, as well as rodent brain, kidney, lung, placenta, prostate, and testis. ESTs have been isolated from a normal prostate library, as well as cancer libraries of the head/neck, ovary, and thyroid. Function: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins. Subcellular Location: 溶血磷脂酸受体蛋白3/EDG7抗体Cell membrane; Multi-pass membrane protein. Tissue Specificity: Most abundantly expressed in prostate, testes, pancreas, and heart, with moderate levels in lung and ovary. No detectable expression in brain, placenta, liver, skeletal muscle, kidney, spleen, thymus, small intestine, colon, or peripheral blood leukocytes. Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 23566 Database links: Entrez Gene: 23566 Human Entrez Gene: 65086 Mouse Entrez Gene: 66025 Rat Omim: 605106 Human SwissProt: Q9UBY5 Human SwissProt: 溶血磷脂酸受体蛋白3/EDG7抗体Q9EQ31 Mouse SwissProt: Q8K5E0 Rat Unigene: 674915 Human Unigene: 155520 Mouse Unigene: 64507 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
溶血磷脂酸受体蛋白3/EDG7抗体产品应用：WB=1:100-500 ELISA=1:2000-5000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 信号转导 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid