维甲酸受体G抗体
规格：1mg/1ml
英文名： RXR gamma
别名： Retinoic acid receptor RXR gamma; MGC109416; NR2B3; Nuclear receptor subfamily 2 group B member 3; OTTHUMP00000060418; Retanoic X receptor gamma; Retinoic acid receptor RXR gamma; Retinoid X receptor
分子量： 51kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RXR Alph
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞核
维甲酸受体G抗体产品介绍：background: Retinoids are metabolites of vitamin A (retinal) and are believed to represent important signaling molecules during vertebrate development and tissue differentiation. Two families of retinoid receptors have been identified. Retinoic acid receptors (RARs) include RAR alpha, RAR beta and RAR gamma, each of which has a high affinity for all trans retinoic acids and belongs to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns through out development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXR alpha, RXR beta and RXR gamma, are activated by 9 cis retinoic acid, a stereo and photoisomer of all trans RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone. Function: Receptor for retinoic acid. Retinoic维甲酸受体G抗体 acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. Subunit: Homodimer. Heterodimer with a RAR molecule. Binds DNA preferentially as a RAR/RXR heterodimer. Subcellular Location: Nucleus. Similarity: Belongs to the nuclear hormone receptor维甲酸受体G抗体 family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain. Gene ID: 6258 Database links: Entrez Gene: 396231 Chicken Entrez Gene: 6258 Human Entrez Gene: 20183 Mouse Entrez Gene: 83574 Rat Omim: 180247 Human SwissProt: P28701 Chicken SwissProt: P48443 Human SwissProt: P28705 Mouse SwissProt: Q5BJR8 Rat Unigene: 26550 Human Unigene: 3475 Mouse Unigene: 40816 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
维甲酸受体G抗体产品应用：ELISA=1:500-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF= （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid