防御素α4抗体
规格：1mg/1ml
英文名： Neutrophil defensin 4
别名： Neutrophil defensin 4; Corticostatin; Defensin alpha 4; Defensin, alpha 4; HNP-4; HP-4; HNP 4; defensin, alpha 4, corticostatin; neutrophil defensin 4 precursor; neutrophil defensin 4 preproprotein; D
分子量： 3.8kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Defensin
交叉反应：Human,
细胞定位：分泌型蛋白
防御素α4抗体产品介绍：background: Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4,防御素α4抗体 is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq]. Function: Has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi. Protects blood cells against infection with HIV-1 (in vitro). Inhibits corticotropin (ACTH)-stimulated corticosterone production. Subunit: 防御素α4抗体Homodimer. Subcellular Location: Secreted. Similarity: Belongs to the alpha-defensin family. Gene ID: 1669 Database links: Entrez Gene: 1669 Human Omim: 601157 Human SwissProt: P12838 Human Unigene: 591391 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
防御素α4抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid