N-乙?;泼?抗体
规格:1mg/1ml
英文名: NAT2
别名: AAC2; Arylamide acetylase 2 (N-acetyltransferase 2, isoniazid inactivation); Arylamide acetylase 2; Arylamine N-acetyltransferase 2; HGNC:7646; N-acetyltransferase 2 (arylamine N-acetyltransferase); A
分子量: 34kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PNAT/NAT
交叉反应:Human, Mouse, Rat, Pig, Horse, Rabbit,
细胞定位:
N-乙酰基转移酶2抗体产品介绍:background: This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided byN-乙?;泼?抗体 RefSeq]. Function: Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens. N-乙?;泼?抗体Subcellular Location: Cytoplasm. Similarity: Belongs to the arylamine N-acetyltransferase family. Gene ID: 10 Database links: Entrez Gene: 10 Human Entrez Gene: 17961 Mouse Omim: 612182 Human SwissProt: P11245 Human SwissProt: P50295 Mouse Unigene: 2 Human Unigene: 4695 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
N-乙?;泼?抗体产品应用:ELISA=1:500-5000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 信号转导 激酶和磷酸酶
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid