细胞表面受体PILRβ抗体
规格:1mg/1ml
英文名: PILRB
别名: PILRB; Paired immunoglobulin-like type 2 receptor beta; Activating receptor PILR beta; Cell surface receptor FDFACT; Cell surface receptor FDFACT1; Cell surface receptor FDFACT2; FDFACT; FDFACT1; FDFA
分子量: 23kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PILR bet
交叉反应:Human,
细胞定位:细胞膜
细胞表面受体PILRβ抗体产品介绍:background: Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. PILRB is the non-ITIM-bearing member of the receptor pair, which has a truncated cytoplasmic tail relative to its ITIM-bearing partner and functions in the activating role. There are three named isoforms produced by alternative splicing. Function: Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system.细胞表面受体PILRβ抗体 PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface. Subcellular Location: Membrane; Single-pass type I membrane protein (Potential). Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain. Gene ID: 29990 Database links: Entrez Gene: 29990 Human Omim: 605342 Human SwissProt: Q9UKJ0 Human 细胞表面受体PILRβ抗体Unigene: 632314 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Ⅱ型成对**球蛋白样受体β蛋白
细胞表面受体PILRβ抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:**学 信号转导 干细胞 细胞膜受体 细胞表面分子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid