抑癌蛋白DKK3抗体
规格:1mg/1ml
英文名: DKK3
别名: Dickkopf 3; Dickkopf homolog 3; Dickkopf related protein 3; Dickkopf related protein 3 Precursor; Dickkopf3; DKK 3; DKK3; hDkk 3; hDkk3; REIC; RIG-like 5-6; RIG-like 7-1; DKK3_HUMAN; Dickkopf 3 homolo
分子量: 36kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human DKK3
交叉反应:Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
细胞定位:分泌型蛋白
抑癌蛋白DKK3抗体产品介绍:background: Dickkopf 3, like DKK1, DKK2, and DKK4, possesses an N terminal signal peptide and 2 conserved cysteine rich domains, which are separated by a linker region and contain 10 cysteine residues each. The second cysteine region has a putative lipid binding function that may facilitate WNT/DKK interactions at the plasma membrane. The linker region contains 50 to 55 amino acids in DKK1, DKK2, and DKK4, whereas in DKK3 it contains only 12 amino acids. All DKKs have several potential sites for cleavage by furin type proteases. Subunit: Interacts with LRP5 and LRP6. Subcellular Location: Secreted. Tissue Specificity: Highest expression in heart, brain, 抑癌蛋白DKK3抗体and spinal cord. Similarity: Belongs to the dickkopf family. Gene ID: 27122 Database links: Entrez Gene: 抑癌蛋白DKK3抗体27122 Human NCBI: 40548393 Human Omim: 605416 Human SwissProt: Q9UBP4 Human Unigene: 292156 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
抑癌蛋白DKK3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 信号转导 转录调节因子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid