CLEC2D蛋白抗体
规格:1mg/1ml
英文名: CLEC2D
别名: C-type lectin domain family 2 member D; C type lectin domain family 2 member D isoform 5; CLAX; LLT1; OCIL; Lectin like NK cell receptor; Lectin like transcript 1; Osteoclast inhibitory lectin; CLC2D_
分子量: 10kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CLEC2D
交叉反应:Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
细胞定位:细胞膜 细胞外基质
CLEC2D蛋白抗体产品介绍:background: This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified, but the full-length nature of every transcript has not been defined. Function: Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans. Subunit: Homodimer or heterodimer;CLEC2D蛋白抗体 disulfide-linked. Subcellular Location: Cell membrane; Single-pass type II membrane protein. Cell surface. Isoform 2, 4: Endoplasmic reticulum. Tissue Specificity: Detected in fetal heart, brain, lung, chondrocytes, perichondrium and osteoblasts, and in ***** splenocytes, thymocytes, lymph-node cells, osteoblasts, growth plate chondrocytes and skeltal muscle overlying the bone (at protein level). Ubiquitous. Detected in thymus, bone marrow, lung, gut, heart, skeletal muscle, ovary, spleen, ileum, liver and kidney. Similarity: Contains 1 C-type lectin domain. Gene ID: CLEC2D蛋白抗体29121 Database links: Entrez Gene: 29121 Human Entrez Gene: 93694 Mouse Entrez Gene: 113937 Rat Omim: 605659 Human SwissProt: Q9UHP7 Human SwissProt: Q91V08 Mouse SwissProt: Q925N7 Rat Unigene: 268326 Human Unigene: 197536 Mouse Unigene: 22573 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CLEC2D蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:10-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:**学 细胞表面分子 t-**细胞
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid