白介素22受体结合蛋白抗体
规格：1mg/1ml
英文名： IL22BP
别名： IL22RA2; Interleukin-22 receptor subunit alpha-2; IL-22 receptor subunit alpha-2; IL-22R-alpha-2; IL-22RA2; Interleukin-22-binding protein; IL-22BP; IL22BP; Cytokine receptor family 2 member 10; CRF2-
分子量： 28(hu)/25(mo, rakDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from humna IL-22BP
交叉反应：Human, Mouse, Rat,
细胞定位：
白介素22受体结合蛋白抗体产品介绍：background: There are two isoforms of IL22 RA2 produce by alternative splicing. Isoform 1 may play a role in establishing and maintaining successful pregnancy. Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). It may play an important role as an IL22 antagonist in the regulation of inflammatory responses. Function: Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses. Isoform 1 may play a role in establishing and maintaining successful pregnancy. Subcellular Location: Secreted. Tissue Specificity: Expressed in placenta, spleen, breast, 白介素22受体结合蛋白抗体skin and lung. Also detected in intestinal tract, testis, brain, heart and thymus. No expression found in prostate, bladder, kidney, ovary, muscle, bone marrow, liver and uterus. Isoform 1 is expressed only in placenta. Isoform 2 is expressed in placenta and breast and at lower level in spleen, skin, thymus and stomach. Similarity: Belongs to the type II cytokine receptor family. Contains 3 fibronectin type-III白介素22受体结合蛋白抗体 domains. Gene ID: 116379 Database links: Entrez Gene: 116379 Human Omim: 606648 Human SwissProt: Q969J5 Human Unigene: 126891 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 白介素22结合蛋白是一种新型的Ⅱ类细胞因子受体家族成员，它能直接结合IL－22，作为IL－22的拮抗剂，发挥着多种生物学功能。
白介素22受体结合蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:50-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 细胞表面分子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid