S100A13抗体
规格：1mg/1ml
英文名： S100A13
别名： Protein S100 A13; S100 calcium binding protein A13; S10AD_HUMAN; Protein S100-A13; S100 calcium-binding protein A13; S100a13.
分子量： 11.5kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human S100A13
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
细胞定位：细胞浆 分泌型蛋白
S100A13抗体产品介绍：background: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is widely expressed in various types of tissues with a high expression level in thyroid gland. In smooth muscle cells, this protein co-expresses with other family members in the nucleus and in stress fibers, suggesting diverse functions in signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] Function: Plays a role in the export of proteins that lack a signal peptide and are secreted by an alternative pathway. Binds two calcium ions per subunit. S100A13抗体Binds one copper ion. Binding of one copper ion does not interfere with calcium binding. Required for the copper-dependent stress-induced export of IL1A and FGF1. The calcium-free protein binds to lipid vesicles containing phosphatidylserine, but not to vesicles containing phosphatidylcholine. Subunit: Homodimer. Part of a copper-dependent multiprotein complex containing S100A13, FGF1 and SYT1. Interacts with FGF1 and SYT1. S100A13抗体Subcellular Location: Cytoplasm. Secreted. Secretion is mediated by exposure to stress and requires copper ions. Tissue Specificity: Expressed in heart and skeletal muscle. Similarity: Belongs to the S-100 family. Contains 1 EF-hand domain. Gene ID: 6284 Database links: Entrez Gene: 6284 Human Omim: 601989 Human SwissProt: Q99584 Human Unigene: 516505 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
S100A13抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid