白介素17受体抗体
规格：1mg/1ml
英文名： IL17A Receptor
别名： IL-17RA; IL17A Receptor; Interleukin-17 receptor A; IL17RA; CDw217; hIL-17R; IL-17RA; IL-17R; MGC10262; IL-17 receptor A; IL-17RA; CD217; IL17 RECEPTOR; IL17FR; AW538159; I17RA_HUMAN.
分子量： 92kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IL-17R (
交叉反应：Human, Mouse, Rat,
细胞定位：细胞膜
白介素17受体抗体产品介绍：background: Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. [provided by RefSeq] Function: Receptor for IL17A and IL17F. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling. Subcellular Location: Membrane; Single-pass type I membrane protein.白介素17受体抗体 Tissue Specificity: Widely expressed. Post-translational modifications: Glycosylated. DISEASE: Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5) [MIM:613953]. CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans. Similarity: Contains 1 SEFIR domain. Gene ID: 23765 Database links:白介素17受体抗体 Entrez Gene: 23765 Human Entrez Gene: 16172 Mouse Omim: 605461 Human SwissProt: Q96F46 Human SwissProt: Q60943 Mouse Unigene: 48353 Human Unigene: 4481 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产白介素17受体抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞膜受体 细胞表面分子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid