缓激肽B2受体抗体
规格:1mg/1ml
英文名: BDKRB2
别名: B2; B2 bradykinin receptor; B2BKR; B2BRA; B2R; BDKR B2; BDKRB 2; Bdkrb2; BK 2; BK 2 receptor; BK R2; BK2; BK2 receptor; BK2R; BKR 2; BKR2; BR B2; Bradykinin receptor b2; Bradykinin receptor beta 2; BR
分子量: 43kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Bdkrb2
交叉反应:Human, Mouse, Rat,
细胞定位:细胞膜
缓激肽B2受体抗体产品介绍:background: Bradykinin increases vascular permeability, dilates blood vessels, contracts non-vascular smooth muscle, and causes pain. This product detects a receptor for bradykinin. The receptor is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. Bradykinin B2 receptor expression has been reported in blood, brain, eye, kidney, liver, lung,prostate, skin, small intestine, synovium, uterus, and vessel. ESTs have been isolated from colon, connective tissue, heart, heart/melanocyte/uterus, kidney, lung, placenta, and thyroid libraries. Function: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. Subunit: Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1. Subcellular Location: Cell membrane;缓激肽B2受体抗体 Multi-pass membrane protein. Tissue Specificity: Ubiquitous. Widespread in normal smooth muscle tissue and neurons. Similarity: Belongs to the G-protein coupled receptor 1 family. Bradykinin receptor subfamily. BDKRB2 sub-subfamily. Gene ID: 624 Database links: Entrez 缓激肽B2受体抗体Gene: 624 Human Entrez Gene: 12062 Mouse Omim: 113503 Human SwissProt: P30411 Human SwissProt: P32299 Mouse Unigene: 654542 Human Unigene: 726620 Human Unigene: 390475 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 缓激肽B2受体目前主要在糖尿病肾病的发生、发展中起着重要作用。
产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-200 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
缓激肽B2受体抗体研究领域:
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid