NK细胞受体2C抗体
规格:1mg/1ml
英文名: NKG2C
别名: Natural killer cell group 2C; natural killer cell protein group 2-C; NKG2-C type II integral membrane protein; NKG2-C-activating NK receptor; NK cell receptor C; CD159 antigen-like family member C; CD
分子量: 26kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NKG2C
交叉反应:Human,
细胞定位:细胞膜
NK细胞受体2C抗体产品介绍:background: Natural killer (NK) cells are lymphocytes that can mediate the lysis of certain tumor cells and virus infected cells without being previously activated. They can also regulate specific humoral and cell mediated immunity. NK cells preferentially express several calcium dependent (C type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C type lectin domain. The KLRC (NKG2) gene family is located within the NKNK细胞受体2C抗体 complex, a region that contains several C type lectin genes preferentially expressed on NK cells. Function: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Subunit: Can form disulfide-bonded heterodimer with CD94. Interacts with TYROBP. Subcellular Location: Membrane; Single-pass type II membrane protein. Tissue Specificity: Natural killer cells. Similarity: Contains 1 C-type lectin domain. Gene ID: 3822 Database links: Entrez Gene: 3822 Human Omim: 602891 Human SwissProt: Q9GME8 Chimpanzee SwissProt:NK细胞受体2C抗体 P26717 Human SwissProt: Q9MZK6 Rhesus monkey Unigene: 591157 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 自然杀伤细胞活化性受体2C
NK细胞受体2C抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:50-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid