利钠肽受体C抗体
规格：1mg/1ml
英文名： NPRC
别名： ANP C; ANPC; ANPRC; Atrial natriuretic peptide C type receptor; Atrionatriuretic peptide receptor C; Natriuretic peptide receptor C/guanylate cyclase C; NPR 3; NPR C; NPR3; NPRC; ANPRC_HUMAN.
分子量： 57kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NPR-C
交叉反应：Human, Mouse, Rat, Cow, Horse,
细胞定位：细胞膜
利钠肽受体C抗体产品介绍：background: Natriuretic peptide receptor C does not exhibit guanylate cyclase activity. There seem to be at least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one (ANPC) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction. Function: Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and 利钠肽受体C抗体skeletal development. Does not have guanylate cyclase activity. Subunit: Homodimer; disulfide-linked. Dimers can also be formed through the C-terminal cysteine of isoform 2. Subcellular Location: Membrane; Single-pass type I membrane protein. Similarity: Belongs to the ANF receptor family. Gene ID: 4883 Database links: Entrez Gene: 281358 Cow Entrez Gene: 4883 Human Entrez Gene: 18162 Mouse Entrez Gene: 25339 Rat Omim: 108962 Human SwissProt: P10730 Cow SwissProt: P17342 Human SwissProt: P70180 Mouse SwissProt: P41740 Rat Unigene: 237028利钠肽受体C抗体 Human Unigene: 619466 Human Unigene: 25259 Mouse Unigene: 11297 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
利钠肽受体C抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 **学 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid