嗅球蛋白1抗体
规格:1mg/1ml
英文名: Noelin
别名: OLFM1; AMY; D2Sut1e; Neuronal olfactomedin-related ER localized protein; Noe1; Noel; Noel1; Noelin1; OlfA; Olfactomedin 1; Olfm1; Pancortin 1; Pancortin.
分子量: 51kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Noelin
交叉反应:Human, Mouse, Rat, Chicken, Horse,
细胞定位:细胞浆
嗅球蛋白1抗体产品介绍:background: The Olfactomedin family comprises a diverse group of secreted glycoproteins, which includes OLFM1 (Noelin-1), OL*** (Noelin-2), OLFM3 (Noelin-3), OLFM4 (Noelin-4), tiarin, pancortin, gliomedin and mycocilin. These proteins are implicated in the development of the nervous system. Specifically, OLFM1 and OL*** expression is observed in the neural plate and neural crest, as well as in the cranial ganglia in mouse at E8-10, and later in brain tissue and in the zone of polarizing activity in the limb. Overexpression of 嗅球蛋白1抗体OLFM1 causes an excess of neural crest emigrations and prolonged neural crest production. OL*** participates in the regulation of the development of the anterior nervous system. An Arg144Gln mutation in OL*** has been implicated as a possible cause for open-angle glaucoma (OAG). Function: Noelins belong to the olfactomedin family, which is comprised of extracellular proteins with proposed roles in neural and neural crest development. Subcellular Location: Endoplasmic reticulum lumen. Similarity: Contains 1 olfactomedin-like domain. Gene ID: 10439 Database links: 嗅球蛋白1抗体Entrez Gene: 395535 Chicken Entrez Gene: 10439 Human Entrez Gene: 56177 Mouse Entrez Gene: 93667 Rat Omim: 605366 Human SwissProt: Q9IAK4 Chicken SwissProt: Q99784 Human SwissProt: O88998 Mouse SwissProt: Q62609 Rat Unigene: 522484 Human Unigene: 43278 Mouse Unigene: 11005 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
嗅球蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid