RNA结合蛋白42抗体
规格:1mg/1ml
英文名: RBM42
别名: MGC10433; RNA binding motif protein 42; RNA binding protein 42.
分子量: 50kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human RBM42
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig,
细胞定位:细胞核 细胞浆
RNA结合蛋白42抗体产品介绍:background: RNA binding motif protein 42 (RBM42) C-terminal domain interacts with HNRNPK C-terminla domain and RNA. RBM42 and HNRNPK are involved in the maintenance of cellular ATP levels during stress, possibly by protecting critical mRNAs. Upon stress response, RBM42 localizes with HNRNPK in cytoplasmic aggregates of stalled translational pre-initiation RNA结合蛋白42抗体complexes called stress granules. There are 4 isoforms produced by alternative splicing. Function: Binds (via the RRM domain) to the 3'-untranslated region (UTR) of CDKN1A mRNA. Subunit: Interacts with HNRNPK. Subcellular Location: Cytoplasmic and Nuclear. Similarity: Belongs to the RRM RBM42 family. Contains 1 RRM (RNA recognition motif) domain. Database links: Entrez Gene: 79171 Human Entrez Gene: RNA结合蛋白42抗体68035 Mouse Entrez Gene: 361545 Rat GenBank: NP_077297.2 Human Omim: 613232 Human SwissProt: Q9BTD8 Human SwissProt: Q91V81 Mouse SwissProt: Q6AXT7 Rat Unigene: 5086 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
RNA结合蛋白42抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:结合蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid