溶质载体转运蛋白家族36成员A3抗体
规格：1mg/1ml
英文名： SLC36A3
别名： FLJ16658; MGC119638; MGC119639; MGC119641; PAT 3; PAT3; Proton/amino acid transporter 3; Solute carrier family 36 (proton/amino acid symporter) member 3; Solute carrier family 36 member 3; TRAMD 2; TR
分子量： 54kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SLC36A3
交叉反应：Human,
细胞定位：细胞膜
溶质载体转运蛋白家族36成员A3抗体产品介绍：Function: Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids. Transports glycine and proline. Inhibited by sarcosine. Tissue Specificity: Abundantly expressed in kidney and muscle. Expressed in the S1 segment of the proximal tubule close to the glomerulus. DISEASE: The disease is caused by mutations affecting the gene represented in this entry. Disease description:A condition characterized by excess of glycine in the urine. In some cases it is associated with renal colic and renal oxalate stones. The disease is caused by mutations affecting distinct genetic loci, including the gene represented in this entry. Mutations in SLC36A2 that retain residual transport activity result in the IG phenotype only when combined with haploinsufficiency of the imino溶质载体转运蛋白家族36成员A3抗体 acid transporter SLC6A20 or deficiency of the neutral amino acid transporter SLC6A19. Additional polymorphisms and mutations in SLC6A18 can contribute to iminoglycinuria in some families. Disease description:A disorder of renal tubular reabsorption of glycine and imino acids (proline and hydroxyproline), marked by excessive levels of all three substances in the urine. Similarity: Belongs to the溶质载体转运蛋白家族36成员A3抗体 amino acid/polyamine transporter 2 family. Database links: Entrez Gene: 285641 Human Omim: 608332 Human SwissProt: Q495N2 Human Unigene: 720893 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
溶质载体转运蛋白家族36成员A3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转运蛋白 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid