RAN结合蛋白10抗体
规格：1mg/1ml
英文名： RANBP10
别名： FLJ31165; KIAA1464; RAN binding protein 10; Ran-binding protein 10; ranbp10; RBP10_HUMAN.
分子量： 67kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RANBP10
交叉反应：Human, Mouse, Rat,
细胞定位：
RAN结合蛋白10抗体产品介绍：Function: Acts as a guanine nucleotide exchange factor (GEF) for RAN GTPase (By similarity). May play an essential role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function (By similarity). May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. In contrast to RANBP9, does not interact with Sos and does not activate the Ras pathway. Subunit: May form homodimers. Interacts with RAN结合蛋白10抗体RAN and RANBP9. Interacts with the HGF receptor MET. Interacts with AR. Interacts with TUBB1. May interact with TUBB5 (By similarity). Tissue Specificity: Broadly expressed, with highest levels in skeletal muscle. Similarity: Belongs to the RANBP9/10 family.RAN结合蛋白10抗体 Contains 1 B30.2/SPRY domain. Contains 1 CTLH domain. Contains 1 LisH domain. Database links: Entrez Gene: 57610 Human Entrez Gene: 74334 Mouse Entrez Gene: 361396 Rat Omim: 614031 Human SwissProt: Q6VN20 Human SwissProt: Q6VN19 Mouse Unigene: 368569 Human Unigene: 4206 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
RAN结合蛋白10抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 结合蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid