RALGPS1蛋白抗体
规格:1mg/1ml
英文名: RALGPS1
别名: Ral GEF with PH domain and SH3 binding motif 1; RalA exchange factor RalGPS1; RALGEF2; RALGPS1A; Ras specific guanine nucleotide releasing factor RalGPS1.
分子量: 62kDa
储存液:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human RALGPS1
交叉反应:Human,
细胞定位:细胞浆 细胞膜
RALGPS1蛋白抗体产品介绍:background: May be involved in cytoskeletal organization (By similarity). May also be involved in the stimulation of transcription in a Ras independent fashion (By similarity). Guanine nucleotide exchange factor for the small GTPase RALA. Six different isoforms have been described. Function: Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization (By similarity). Guanine nucleotide exchange factor for. Subunit: Interacts with the SH3 domains of GRB2, RALGPS1蛋白抗体NCK1, PLCG1 and SRC. Subcellular Location: Cell Membrane and Cytoplasmic. Tissue Specificity: Widely expressed (at protein level). Isoform 2 is expressed in brain, colon, kidney, pancreas, prostate, skeletal muscle, small intestine, testis, thymus and uterus. Isoform 1 is expressed at high levels in heart and testis and at lower levels in brain, pancreas, skeletal muscle, small intestine and thymus. Database links: Entrez Gene:RALGPS1蛋白抗体 9649 Human SwissProt: Q5JS13 Human Unigene: 648175 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
RALGPS1蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid