硒蛋白N抗体
规格：1mg/1ml
英文名： SEPN1/Selenoprotein N
别名： CFTD; MDRS1; RSMD1; RSS; Selenoprotein N; Selenoprotein N, 1; SelN; SELN_HUMAN; sepn1.
分子量： 58kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SEPN1/Se
交叉反应：Human, Mouse, Rat,
细胞定位：
硒蛋白N抗体产品介绍：Subcellular Location: Endoplasmic reticulum membrane. Probably membrane-associated. Tissue Specificity: Isoform 1 and isoform 2 are expressed in skeletal muscle, brain, lung and placenta. Isoform 2 is also expressed in heart, diaphragm and stomach. Post-translational modifications: N-glycosylated (isoform 2). DISEASE: Defects in SEPN1 are the cause of myopathy SEPN1-related (M-SEPN1) [MIM:602771]. A group of neuromuscular disorders consisting of four nosological entities: classic multiminicore disease (MmD), 硒蛋白N抗体rigid spine muscular dystrophy 1 syndrome (RSMD1), desmin-related myopathy with Mallory body-like inclusions (MB-DRM) and congenital fiber-type disproportion. All are clinically characterized by poor axial muscle strength, scoliosis and neck weakness, and a variable degree of spinal rigidity. Early ventilatory insufficiency can lead to death by respiratory failure. Similarity: Contains 1 EF-hand domain. Database links: 硒蛋白N抗体Entrez Gene: 57190 Human Entrez Gene: 74777 Mouse Entrez Gene: 362624 Rat Omim: 606210 Human SwissProt: Q9NZV5 Human Unigene: 323396 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
硒蛋白N抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid