头状肾细胞癌PRCC抗体
规格：1mg/1ml
英文名： PRCC/Papillary renal cell carcinoma
别名： Papillary renal cell carcinoma (Translocation associated), isoform CRA_b; Papillary renal cell carcinoma translocation-associated gene protein; PRCC; PRCC_HUMAN; Proline rich protein PRCC; Proline-ric
分子量： 52kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PRCC/Pap
交叉反应：Human, Mouse,
细胞定位：细胞核
头状肾细胞癌PRCC抗体产品介绍：background: This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.[provided by RefSeq, Aug 2010] Function: May regulate cell cycle progression头状肾细胞癌PRCC抗体 through interaction with MAD2L2. Subunit: Interacts with MAD2L2; the interaction is direct. Subcellular Location: Nucleus. Tissue Specificity: Ubiquitous in fetal and ***** tissues. DISEASE: Note=A chromosomal aberration involving PRCC is found in patients with papillary renal cell carcinoma. Translocation t(X;1)(p11.2;q21.2) with TFE3. Database links: Entrez Gene: 5546 Human Entrez Gene: 94315 Mouse 头状肾细胞癌PRCC抗体Omim: 179755 Human SwissProt: Q92733 Human Unigene: 516948 Human Unigene: 35089 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产头状肾细胞癌PRCC抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid