4-羟化酶α1抗体
规格:1mg/1ml
英文名: P4HA1
别名: 2-oxoglutarate-4-dioxygenase subunit alpha-1; 4-hydroxylase, alpha I subunit; 4-PH alpha-1; P4HA; P4HA1; P4HA1_HUMAN; Procollagen-proline; Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-
分子量: 60kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human P4HA1
交叉反应:Human, Mouse, Rat, Chicken, Cow, Zebrafish,
细胞定位:
4-羟化酶α1抗体产品介绍:background: This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] Function: Catalyzes the post-translational formation 4-羟化酶α1抗体of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. Subcellular Location: Endoplasmic reticulum lumen. Similarity: Belongs to the P4HA family. Contains 1 Fe2OG dioxygenase domain. Contains 1 TPR repeat. Database links: Entrez Gene: 5033 Human Entrez Gene: 18451 Mouse Entrez Gene: 64475 Rat SwissProt: P13674 Human SwissProt: Q60715 Mouse SwissProt: P54001 Rat Unigene: 500047 4-羟化酶α1抗体Human Unigene: 593005 Human Unigene: 2212 Mouse Unigene: 8531 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
4-羟化酶α1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid