脑特异性POU结构域同源盒基因3C抗体
规格：1mg/1ml
英文名： POU4F3
别名： Brain specific homeobox/POU domain protein 3C; Brain-3C; Brain-specific homeobox/POU domain protein 3C; BRN 3C; Brn-3C; BRN3C; class 4; DFNA 15; DFNA15; MGC138412; PO4F3_HUMAN; POU class 4 homeobox 3;
分子量： 37kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human POU4F3
交叉反应：Human, Mouse, Rat,
细胞定位：细胞核
脑特异性POU结构域同源盒基因3C抗体产品介绍：background: This gene encodes a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. This protein is found in the retina and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in this gene are the cause of non-syndromic sensorineural deafness autosomal dominant type 15. [provided by RefSeq, Mar 2009] Function: May play a role in determining or maintaining the identities of a small subset of visual system neurons. Subcellular Location: Nucleus. Tissue Specificity: Brain. Seems to be specific to the retina. DISEASE: Defects in POU4F3 are the cause of deafness autosomal dominant type 15 (DFNA15) [MIM:602459].脑特异性POU结构域同源盒基因3C抗体 DFNA15 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. Similarity: Belongs to the POU transcription factor family. Class-4 subfamily. Contains 1 homeobox DNA-binding domain. Contains 1 POU-specific domain. Database links: Entrez Gene: 395521 Chicken Entrez Gene: 5459 Human Entrez Gene: 18998 Mouse Entrez Gene: 364855 Rat Entrez Gene: 30534 Zebrafish Omim: 602460 Human脑特异性POU结构域同源盒基因3C抗体 SwissProt: P55968 Chicken SwissProt: Q15319 Human SwissProt: Q63955 Mouse SwissProt: Q90435 Zebrafish Unigene: 553499 Human Unigene: 221181 Mouse Unigene: 488204 Mouse Unigene: 218181 Rat Unigene: 93311 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
脑特异性POU结构域同源盒基因3C抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 神经生物学 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid