碳酸氢钠协同转运蛋白4-A11抗体
规格：1mg/1ml
英文名： SLC5A11
别名： homolog of rabbit KST1; KST1; Na(+)/myo-inositol cotransporter 2; na+/myo-inositol cotransporter 2; putative sodium-coupled cotransporter RKST1; RKST1; SC5AB_HUMAN; SGLT6; SLC5A11; SMIT2; sodium-depen
分子量： 74kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SLC5A11
交叉反应：Human, Mouse,
细胞定位：细胞膜
碳酸氢钠协同转运蛋白4-A11抗体产品介绍：background: Cotransporters, such as SLC5A11, represent a major class of proteins that make use of ion gradients to drive active transport for the cellular accumulation of nutrients, neurotransmitters, osmolytes, and ions Roll et al. (2002) [PubMed 12039040].[supplied by OMIM, Mar 2008] Function: Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D-chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D-xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney. Subcellular碳酸氢钠协同转运蛋白4-A11抗体 Location: Membrane. Tissue Specificity: Highest expression in heart, skeletal muscle, kidney, liver and placenta. Weaker expression in brain, colon, spleen, lung and peripheral blood leukocytes. Similarity: Belongs to the sodium:solute symporter (SSF) 碳酸氢钠协同转运蛋白4-A11抗体(TC 2.A.21) family. Database links: Entrez Gene: 115584 Human Omim: 610238 Human SwissProt: Q8WWX8 Human Unigene: 164118 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
碳酸氢钠协同转运蛋白4-A11抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid