RNA聚合酶II相关因子PAF1抗体
规格:1mg/1ml
英文名: PAF1
别名: F23149 1; FLJ11123; hPAF1; PAF 1; PAF1; Paf1 RNA polymerase II associated factor homolog; PAF1_HUMAN; Pancreatic differentiation protein 2; PD 2; PD2; PD2 protein; RNA polymerase II associated factor
分子量: 80kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PAF1
交叉反应:Human, Mouse, Rat,
细胞定位:细胞核
RNA聚合酶II相关因子PAF1抗体产品介绍:background: This gene encodes a subunit of the polymerase associated factor (PAF1) complex. The PAF1 complex interacts with RNA polymerase II and plays a role in transcription elongation as well as histone modifications including ubiquitylation and methylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012] Function: The mammalian PAF1 complex is a multifunctional complex. The PAF1 complex interacts with RNA polymerase II and may be involved in both initiation and elongation, and in histone methylation and RNA processing. Has oncogenic activity in vivo RNA聚合酶II相关因子PAF1抗体and in vitro. Subcellular Location: Nucleus. Punctuate distribution throughout the nucleus except in nucleoli and the perinuclear chromatin. Similarity: Belongs to the PAF1 family. Database links: Entrez Gene: 54623 Human Entrez Gene: 54624 Mouse Entrez Gene: 361531 Rat Entrez Gene: 446278 Xenopus laevis Omim: 610506 Human SwissProt: Q8N7H5 Human SwissProt: Q8K2T8 Mouse SwissProt: Q4V886 RNA聚合酶II相关因子PAF1抗体Rat SwissProt: A2BD83 Xenopus laevis Unigene: 466714 Human Unigene: 7916 Mouse Unigene: 161558 Rat Unigene: 29705 Xenopus laevis Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
RNA聚合酶II相关因子PAF1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid