水通道蛋白-9抗体
规格：1mg/1ml
英文名： AQP9
别名： aquaporin Protein-9; Aquaporin 9; AQP 9; AQP9; Aquaporin9; HsT 17287; HsT17287; Small solute channel 1; SSC 1; SSC1; Aquaporin-9; AQP-9; Aquaglyceroporin-9; AQP9_HUMAN.
分子量： 32kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human AQP9
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, Guinea Pig,
细胞定位：细胞膜
水通道蛋白-9抗体产品介绍：background: Water is a critical component of all living cells. Interestingly, tissue membranes show a great degree of water permeability. Mammalian red cells, renal proximal tubules, and descending thin limb of Henle are extraordinarily permeable to water. Water crosses hydrophobic plasma membranes either by simple diffusion or through a facilitative transport mechanism mediated by special protein "aquaporin". A new member of AQP family, Aquaporin-9 (AQP9), has been cloned from human leukocytes by homology cloning (Ishibashi et al. 1997). It is mostly homologous with AQP3 and AQP7 (54-48% identity). AQP9 (295 AA) is primarily expressed in peripheral leukocytes, and lesser amounts in liver, lung and spleen. AQP9 is permeable to water and urea. Unlike AQP3 and AQP7, it did not facilitate glycerol transport. AQP families of proteins are predicted to contain six transmembrane domains. The N and C-terminus are predicted to be cytoplasmic. A new member of the AQP family, AQP9, has been cloned from human leukocytes. It is homologous with AQP3 and AQP7 (54-48% identity). AQP9 (295aa) is primarily expressed in peripheral leukocytes, and in lesser amounts in liver, lung and spleen. AQP9 is permeable to water and urea. Unlike AQP3 and 水通道蛋白-9抗体AQP7, it does not facilitate glycerol transport. AQP families of proteins are predicted to contain six transmembrane domains. The N and C-terminus are predicted to be cytoplasmic. Function: Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na(+), K(+), Cl(-), and deprotonated monocarboxylates are excluded. Also permeable to urea and glycerol. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Highly expressed in peripheral leukocytes. Also expressed in liver, lung, and spleen. Similarity: Belongs to the 水通道蛋白-9抗体MIP/aquaporin (TC 1.A.8) family. Gene ID: 366 Database links: Entrez Gene: 366 Human Omim: 602914 Human SwissProt: O43315 Human Unigene: 104624 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. br> AQP9是一种选择性水通透膜转运蛋白，属于主体内在蛋白家族的成员之一。AQP9不但对水具有通透性，而且对其它一些中性溶质也具有通透性。
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:50-300 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗水通道蛋白-9抗体原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid