胆汁酸结合蛋白DDH2抗体
规格:1mg/1ml
英文名: AKR1C2
别名: 2-dihydrobenzene-1; 2-diol dehydrogenase; 3 alpha HSD3; 3 alpha hydroxysteroid dehydrogenase type III; 3-alpha-HSD3; AK1C2_HUMAN; AKR1C pseudo; AKR1C2; Aldo keto reductase family 1 member C2; Aldo-ket
分子量: 37kDa
储存液:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human AKR1C2
交叉反应:Human, Mouse, Rat,
细胞定位:细胞浆
胆汁酸结合蛋白DDH2抗体产品介绍:background: Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha-DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability. Function: Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha-DHT) to 5-alpha-androstane-3-alpha,17-beta-diol胆汁酸结合蛋白DDH2抗体 (3-alpha-diol). Has a high bile-binding ability. Subcellular Location: Cytoplasm (Potential). Tissue Specificity: Expressed in fetal testes. Expressed in fetal and ***** adrenal glands. DISEASE: Defects in AKR1C2 are a cause of 46,XY sex reversal type 8 (SRXY8) [MIM:614279]. A disorder of sex development. Affected individuals have a 46,XY karyotype but present as phenotypically normal females. Similarity胆汁酸结合蛋白DDH2抗体: Belongs to the aldo/keto reductase family. Gene ID: 52895 Database links: SwissProt: P52895 Human SwissProt: Q04828 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胆汁酸结合蛋白DDH2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 肿瘤细胞生物标志物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid