神经细胞粘附蛋白NGN抗体
规格：1mg/1ml
英文名： Neogenin
别名： NGN; Neo1; Neo 1; Neogenin; NEO1_HUMAN.
分子量： 156kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Neogenin
交叉反应：Human, Mouse, Rat, Dog, Cow, Sheep,
细胞定位：细胞膜
神经细胞粘附蛋白NGN抗体产品介绍：background: This gene encodes a cell surface protein that is a memberof the immunoglobulin superfamily. The encoded protein consists offour N-terminal immunoglobulin-like domains, six fibronectin typeIII domains, a transmembrane domain and a C-terminal internaldomain that shares homology with the tumor suppressor candidategene DCC. This protein may be involved in cell growth anddifferentiation and in cell-cell adhesion. Defects in this gene areassociated with cell proliferation in certain cancers. Alternatesplicing results in multiple transcript variants. [provided byRefSeq, Feb 2010]. Function: Neogenin is one of several netrin-binding proteins. Neogenin functions as an Repulsive Guidance Molecule (RGM) receptor; RGM is implicated in axonal guidance and neural tube closure. Subunit: Interacts with RGMA. Interacts with MYO10 Subcellular Location: Cell membrane; Single-pass type I membraneprotein. Tissue Specificity: Widely expressed and also in cancer celllines. Similarity: Belongs to the immunoglobulin superfamily. DCC family. Contains 6 fibronectin type-III domains. Contains 4神经细胞粘附蛋白NGN抗体 Ig-like C2-type (immunoglobulin-like)domains. Gene ID: 4756 Database links: Entrez Gene: 4756 Human Entrez Gene: 18007 Mouse Entrez Gene: 81735 Rat Omim: 601907 Human SwissProt: Q92859 Human SwissProt: P97798 Mouse SwissProt: P97603 Rat Unigene: 388613 Human Unigene: 42249 Mouse Unigene: 10667 Rat Important Note: This product as supplied is intended for research 神经细胞粘附蛋白NGN抗体use only, not for use in human, therapeutic or diagnostic applications.
神经细胞粘附蛋白NGN抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 细胞粘附分子 细胞分化
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid