HRAS样抑制因子3抗体
规格:1mg/1ml
英文名: Hrasls3
别名: H rev 107 protein homolog; HRAS like suppressor 3; HREV107 3; HREV107; Renal carcinoma antigen NY REN 65; Adipose specific phospholipase A2; Group XVI phospholipase A2; HREV107; HRSL3_MOUSE; AdPLA; HR
分子量: 18kDa
储存液:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Hrasls3
交叉反应:Human, Mouse, Rat,
细胞定位:细胞膜
HRAS样抑制因子3抗体产品介绍:background: HRASLS3 specifically catalyzes the release of fatty acids from phospholipids in adipose tissue and also has a weak lysophospholipase activity. It is a tumor suppressor that may be involved in interferon-dependent cell death. Function: Exhibits PLA1/2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Specifically catalyzes the release of fatty acids from phospholipids in adipose tissue. N-and O-acylation activity is hardly detectable. Also has weak lysophospholipase activity. Subunit: Interacts with PPP2R1A; this interaction might decrease PP2A activity. Subcellular Location: Membrane; Single-pass membrane protein (Potential). Cytoplasm. Cytoplasm,HRAS样抑制因子3抗体 perinuclear region. Tissue Specificity: Ubiquitously expressed in normal tissues but down-regulated in primary carcinomas or in many cell lines derived from tumors. Highly expressed in white adipose tissue and in adipocytes. Expressed at lower levels in brown adipose tissue. Similarity: Belongs to the H-rev107 family. Gene ID: 225845 Database links: Entrez Gene: 11145 Human Entrez Gene: 225845 Mouse HRAS样抑制因子3抗体Omim: 613867 Human SwissProt: P53816 Human SwissProt: Q8R3U1 Mouse Unigene: 502775 Human Unigene: 274810 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
HRAS样抑制因子3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:**学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid