9号染色体开放阅读框3抗体
规格:1mg/1ml
英文名: C9orf3
别名: Aminopeptidase O; AP O; APO; Chromosome 9 open reading frame 3;AMPO_HUMAN.
分子量: 94kDa
储存液:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human C9orf3
交叉反应:Human, Mouse, Rat, Chicken,
细胞定位:细胞浆
9号染色体开放阅读框3抗体产品介绍:background: C9orf3 is an aminopeptidase and belongs to the M1 family of metallopeptidases or gluzincins. Aminopeptidases catalyze the hydrolysis of amino acid residues from the N-terminus of peptide or protein substrates. C9orf3 is able to cleave angiotensin III to generate angiotensin IV, a bioactive peptide of the renin-angiotensin pathway but not able to cleave angiotensin I and angiotensin II. It may play a role in the proteolytic processing of bioactive peptides in tissues where it is expressed. C9orf3 is predominantly expressed in pancreas, placenta, liver, testis and heart and at lower level in brain, lung and kidney. There are four named isoforms. Function: Aminopeptidases catalyze the hydrolysis of amino acid residues from the N-terminus of peptide or protein substrates. Able to cleave angiotensin 9号染色体开放阅读框3抗体III to generate angiotensin IV, a bioactive peptide of the renin-angiotensin pathway. Not able to cleave angiotensin I and angiotensin II. May play a role in the proteolytic processing of bioactive peptides in tissues such as testis and heart. Subcellular Location: Cytoplasm (Potential). Tissue Specificity: Predominantly expressed in pancreas, placenta, liver, testis and heart. Expressed at lower level in 9号染色体开放阅读框3抗体brain, lung and kidney. Similarity: Belongs to the peptidase M1 family. Gene ID: 84909 Database links: Entrez Gene: 84909 Human SwissProt: Q8N6M6 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
9号染色体开放阅读框3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid