卵母细胞TRO抗体
规格:1mg/1ml
英文名: Magphinin
别名: KIAA1114; MAGE d3; TROP_HUMAN; MAGE D3 antigen; MAGE superfamily protein; MAGED3; Magphinin; Melanoma Antigen Family D, 3; OTTHUMP00000180629; OTTHUMP00000180636; TRO.
分子量: 144kDa
储存液:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Magphini
交叉反应:Human, Mouse, Rat,
细胞定位:
卵母细胞TRO抗体产品介绍:background: This gene encodes a membrane protein that mediates apical cell adhesion between trophoblastic cells and luminal epithelial cells of the endometrium and is implicated in the initial attachment during the process of embryo implantation. This gene is related to the MAGED gene family by sequence similarity and chromosome location. Multiple alternatively spliced transcript variants have been found for this gene; however, the full-length nature of some variants has not been defined. Trophinin is directly responsible for homophilic cell adhesion, and could be involved with bystin and tastin in a cell adhesion molecule complex that mediates an initial attachment of the blastocyst to uterine epithelial cells at the time of the embryo implantation. Function: Could be involved with bystin and tastin in a cell adhesion molecule complex that mediates an initial attachment of the blastocyst to uterine epithelial cells at the time of the embryo implantation. Directly responsible for卵母细胞TRO抗体 homophilic cell adhesion. Subunit: Directly binds bystin, and indirectly tastin. Tissue Specificity: Strong expression at implantation sites. Found in the placenta from the sixth week of pregnancy. Was localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the level decreased and then disappeared from placental villi. Also found in macrophages. Similarity: Contains 1 MAGE domain. Gene ID: 56191 Database links: Entrez Gene: 56191 Human Entrez Gene: 7216 Human Omim: 卵母细胞TRO抗体300132 Human SwissProt: Q12816 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
卵母细胞TRO抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 发育生物学 细胞粘附分子 肿瘤细胞生物标志物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid