腺苷酸环化酶3抗体
规格：1mg/1ml
英文名： ADCY3
别名： A cyclase III; AC3; adenylate cyclase 3; Adenylate cyclase type III; ADCY3_HUMAN; Adenylate cyclase type 3; ATP pyrophosphate-lyase 3; AC-III; Adenylate cyclase, olfactive type; AC3.
分子量： 126kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ADCY3
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
细胞定位：细胞膜
腺苷酸环化酶3抗体产品介绍：background: The cAMP synthesizing enzymes are found in two forms: cytosolic (soluble) and membrane-bound (particulate). Stimulation of adenylate cyclases produce cAMP form ATP in response to the activation of GPCRs by various hormones, neurotransmitters and other regulatory molecules. cAMP, in subsequent steps down the signal transduction pathway, can stimulate cAMP-dependent protein kinase A (cPKA), and several other target molecules. Activation of cPKA can phosphorylate a broad range of substrates that regulate various metabolic pathways, gene expression, and affect memory functions etc. The stimulation of adenylate cyclases starts with腺苷酸环化酶3抗体 interactions with GPCRs mediated signals initiated by Gs and Gi heterotrimeric G-proteins. Function: Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, and skeletal muscle. Similarity: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Contains 2 guanylate cyclase domains. Gene ID: 109 Database links: Entrez Gene: 109 Human Entrez Gene: 104111 Mouse Entrez Gene: 64508腺苷酸环化酶3抗体 Rat Omim: 600291 Human SwissProt: O60266 Human SwissProt: Q8VHH7 Mouse SwissProt: P21932 Rat Unigene: 727540 Human Unigene: 70546 Mouse Unigene: 87800 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产腺苷酸环化酶3抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 染色质和核信号 信号转导 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid