胞粘蛋白3抗体
规格：1mg/1ml
英文名： Cytohesin 3
别名： CYTH3; ARF nucleotide-binding site opener 3; ARNO3; ARNO3 protein; CYH3_HUMAN; Cyth3; Cytohesin-3; General receptor of phosphoinositides 1; Grp1; PH; PH, SEC7 and coiled-coil domain-containing protein
分子量： 46kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Cytohesi
交叉反应：Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
胞粘蛋白3抗体产品介绍：background: This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition 胞粘蛋白3抗体to acting on ARF1. [provided by RefSeq, Jul 2008] Function: Promotes guanine-nucleotide exchange on ARF1. Promotes the activation of ARF through replacement of GDP with GTP. Subcellular Location: Cell membrane. Tissue Specificity: Almost absent from liver, thymus and peripheral blood lymphocytes. Similarity: Contains 1 PH domain. Contains 1 SEC7 domain. Gene ID: 9265 Database links: Entrez Gene: 9265 Human Entrez Gene: 19159 Mouse Entrez Gene: 116693 Rat Omim: 605081 Human SwissProt: O43739 Human SwissProt: O08967 Mouse SwissProt: P97696 Rat 胞粘蛋白3抗体Unigene: 487479 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胞粘蛋白3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞粘附分子 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid