钙激活氯通道调节蛋白4抗体
规格：1mg/1ml
英文名： CLCA4
别名： Cl30 kDa form; CaCC-2; Calcium-activated chloride channel family member 4; Calcium-activated chloride channel protein 2; Calcium-activated chloride channel regulator 4; Clca4; CLCA4_HUMAN; hCaCC-2; CL
分子量： 110kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from mouse CLCA4
交叉反应：Mouse, Rat,
细胞定位：细胞膜
钙激活氯通道调节蛋白4抗体产品介绍：background: The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Alternative splicing results in multiple transcript variants, only one of which is thought to be protein coding. [provided by RefSeq, Dec 2008] Function: May be involved in mediating calcium-activated chloride conductance. Subcellular Location: Cell membrane; Single-pass membrane protein. Apical cell membrane. Secreted. Note=The C-terminus 30 kDa form is anchored to the membrane. The N-terminus 110 kDa form is released from the membrane triggered by an unknown stimulus. Associated with the microvilli of non-goblet cell enterocytes in the small and large intestine. Co-localizes with CFTR. Tissue Specificity: Primarily 钙激活氯通道调节蛋白4抗体expressed in the digestive tract, mainly in colon. Detected in smaller amounts in brain, urogenital organs, testis, and salivary and mammary glands. Highly expressed in the epithelial layer and submucosal gland of the inferior turbinate mucosa. Lower levels in the epithelial layer of nasal polyp. Post-translational modifications: N-Glycosylated. Processed at a monobasic residue to yield a larger N-terminal and a smaller 钙激活氯通道调节蛋白4抗体C-terminal cleavage products of 90 to 110 and 30 to 35 kDa, respectively. Similarity: Belongs to the CLCR family. Contains 1 VWFA domain. Gene ID: 99663 Database links: Entrez Gene: 22802 Human Gene ID: 99663 Mouse SwissProt: Q14CN2 Human Unigene: 567422 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
钙激活氯通道调节蛋白4抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：信号转导 通道蛋白 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid