代谢型谷氨酸受体2
规格：1mg/1ml
英文名： mGluR2
别名： GRM2_HUMAN; Metabotropic glutamate receptor 2; mGluR2.
分子量： 94kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human mGluR2
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
细胞定位：
代谢型谷氨酸受体2产品介绍：Function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization. {ECO:0000269|PubMed:18297054, ECO:0000269|PubMed:22300836, ECO:0000269|PubMed:23129762, ECO:0000269|PubMed:7620613}. Subunit: Interacts with GRASP (By similarity). Interacts with HTR2A. {ECO:0000250, ECO:0000269|PubMed:18297054, ECO:0000269|PubMed:22300836, ECO:0000269|PubMed:23129762}. Subcellular Location: Cell membrane; Multi-pass membrane protein. 代谢型谷氨酸受体2Cell junction, synapse {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Tissue Specificity: Detected in brain cortex (at protein level). Widely expressed in different regions of the ***** brain as well as in fetal brain. {ECO:0000269|PubMed:18297054}. Similarity: Belongs to the G-protein coupled receptor 3 family. Gene ID: 2912 Database links: Entrez Gene: 2912 Human Entrez Gene: 108068 Mouse Entrez Gene: 24415 Rat Omim: 604099 Human SwissProt: Q14416 Human SwissProt: Q14BI2 Mouse SwissProt: P31421 Rat Unigene: 121510 Human Unigene: 代谢型谷氨酸受体2410822 Mouse Unigene: 424639 Mouse Unigene: 9681 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产代谢型谷氨酸受体2品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学 通道蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid