MYC启动子结合蛋白1抗体
规格：1mg/1ml
英文名： ENO1
别名： 2 phospho D glycerate hydro lyase; Alpha enolase 1; Alpha enolase; C myc promoter binding protein; EC 4.2.1.11; ENO1L1; Enolase 1 (alpha); Enolase 1 (alpha) like 1; Enolase 1; MBP 1; MBP1; MBPB1; MPB
分子量： 47kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ENO1
交叉反应：Human,
细胞定位：
MYC启动子结合蛋白1抗体产品介绍：background: ENO1 encodes one of three enolase isoenzymes found in mammals; it encodes alpha-enolase, a homodimeric soluble enzyme, and also encodes a shorter monomeric structural lens protein, tau-crystallin. The two proteins are made from the same message. The full length protein, the isoenzyme, is found in the cytoplasm. The shorter protein is produced from an alternative translation start, is localized to the nucleus, and has been found to bind to an element in the c-myc promoter. A pseudogene has been identified that is located on the other arm of the same chromosome. Function: Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. Subunit: Mammalian enolase is composed of 3 isozyme subunits, alpha, beta and gamma, MYC启动子结合蛋白1抗体which can form homodimers or heterodimers which are cell-type and development-specific. ENO1 interacts with PLG in the neuronal plasma membrane and promotes its activation. The C-terminal lysine is required for this binding. Subcellular Location: Cytoplasm. Cell membrane. Cytoplasm, myofibril, sarcomere, M line. Isoform MBP-1: Nucleus. Tissue Specificity: The alpha/alpha homodimer is expressed in embryo and in most ***** tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the MYC启动子结合蛋白1抗体gamma/gamma homodimer in neurons. Similarity: Belongs to the enolase family. Gene ID: 2023 Database links: Entrez Gene: 2023 Human Omim: 172430 Human SwissProt: P06733 Human Unigene: 517145 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MYC启动子结合蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid