G蛋白偶联受体106抗体
规格：1mg/1ml
英文名： GPR106
别名： G protein coupled receptor 106; G-protein coupled receptor 106; G protein coupled receptor affecting testicular descent; GPR106; GPR-106; GREAT; INSL3R; Leucine rich repeat containing G protein couple
分子量： 86kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GPR106
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
G蛋白偶联受体106抗体产品介绍：background: This gene encodes a member of the GPCR (G protein-coupled, 7-transmembrane receptor) family. Mutations in this gene are associated with cryptorchidism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]. Function: The activity of this relaxin receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP and may also be a receptor for Leydig insulin-like peptide. LGR8 has been reported in blood, bone marrow, brain, kidney, muscle, testis, thyroid, and uterus. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed mainly in the brain, kidney, muscle, testis, thyroid, uterus, peripheral blood cells and bone marrow. DISEASE: Defects in G蛋白偶联受体106抗体RXFP2 are a cause of cryptorchidism (CRYPTO) [MIM:219050]; also known as impaired testicular descent. It is one of the most frequent congenital abnormalities in humans, involving 2-5% of male births. Cryptorchidism is associated with increased risk of infertility and testicular cancer. Similarity: Belongs to the G-protein coupled receptor 1 family. Contains 1 LDL-receptor class A domain. Contains 10 LRRG蛋白偶联受体106抗体 (leucine-rich) repeats. Gene ID: 122042 Database links: Entrez Gene: 122042 Human Entrez Gene: 140498 Mouse Entrez Gene: 363866 Rat Omim: 606655 Human SwissProt: Q8WXD0 Human SwissProt: Q91ZZ5 Mouse Unigene: 680763 Human Unigene: 444643 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
G蛋白偶联受体106抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 细胞膜受体 ***病 G蛋白偶联受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid