血管内皮细胞生长抑制蛋白vegi抗体
规格：1mg/1ml
英文名： TL1A
别名： MGC129934; MGC129935; TL1 A; tl1; tl1a; tnf ligand related molecule 1; TNF ligand-related molecule 1; tnf superfamily ligand tl1a; TNF15_HUMAN; tnfsf15; Tumor necrosis factor (ligand) superfamily memb
分子量： 28kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TL1A
交叉反应：Human, Mouse, Rat,
细胞定位：细胞膜 分泌型蛋白
血管内皮细胞生长抑制蛋白vegi抗体产品介绍：background: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011] Function: Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. 血管内皮细胞生长抑制蛋白vegi抗体Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. Subunit: Homotrimer. Subcellular Location: Secreted and Membrane. Tissue Specificity: Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon. Similarity: Belongs to the血管内皮细胞生长抑制蛋白vegi抗体 tumor necrosis factor family. Gene ID: 9966 Database links: Entrez Gene: 9966 Human Entrez Gene: 326623 Mouse Entrez Gene: 252878 Rat Omim: 604052 Human SwissProt: O95150 Human SwissProt: Q5UBV8 Mouse SwissProt: Q8K3Y7 Rat Unigene: 241382 Human Unigene: 208152 Mouse Unigene: 84873 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
血管内皮细胞生长抑制蛋白vegi抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid