线粒体内膜转位同源蛋白50抗体

规格：1mg/1ml

英文名： TIMM50

别名： Homolog of yeast Tim50; Import inner membrane translocase subunit TIM 50; Import inner membrane translocase subunit TIM50; Import inner membrane translocase subunit TIM50 mitochondrial; MGC102733; Mit

分子量： 35kDa

储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型：Polyclonal

亚型：IgG

纯化方法：affinity purified by Protein A

**原：KLH conjugated synthetic peptide derived from human TIMM50

交叉反应：Human, Mouse, Rat,

细胞定位：

线粒体内膜转位同源蛋白50抗体产品介绍：Function: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. Isoform 2 may participate in the release of snRNPs and SMN from the Cajal body. Subunit: Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50; within this complex, directly interacts with TIMM23. The complex interacts with the TIMM44 component of the PAM complex and with DNAJC15. Subcellular Location: Mitochondrion inner membrane and Nucleus speckle. Nuclear and enriched in speckles with snRNPs. Tissue Specificity: Widely expressed. Expressed at higher 线粒体内膜转位同源蛋白50抗体level in brain, kidney and liver (at protein level). Similarity: Belongs to the TIM50 family. 线粒体内膜转位同源蛋白50抗体Contains 1 FCP1 homology domain. Gene ID: 92609 Database links: Entrez Gene: 92609 Human Entrez Gene: 66525 Mouse Entrez Gene: 685725 Rat Omim: 607381 Human SwissProt: Q3ZCQ8 Human SwissProt: Q9D880 Mouse Unigene: 590956 Human Unigene: 597106 Human Unigene: 167913 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

线粒体内膜转位同源蛋白50抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域：细胞生物  信号转导  转运蛋白  

储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源： Rabbit

外观： Lyophilized or Liquid

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