癌/睾丸抗原63
规格：1mg/1ml
英文名： PASD1/CT63
别名： Cancer/testis antigen 63; CT63; OX-TES-1; PAS domain containing 1; PAS domain-containing protein 1; PASD1; PASD1_HUMAN.
分子量： 70kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PASD1/CT
交叉反应：Human,
细胞定位：细胞核
癌/睾丸抗原63品介绍：background: This gene encodes a protein that is thought to function as a transcription factor. The protein is a cancer-associated antigen that can stimulate autologous T-cell responses, and it is therefore considered to be a potential immunotherapeutic target for the treatment of various hematopoietic malignancies, including diffuse large B-cell lymphoma. [provided by RefSeq, May 2010] Function: May function as a transcription factor. Subcellular Location: Nucleus. Tissue Specificity: Testis-specific. Found in histologically normal tissues from patients with uterus, lung and small intestine cancers. Widespread expression seen in solid tumors and diffuse large B-cell lymphoma癌/睾丸抗原63 (DLBCL)-derived cell lines. Isoform 2 is expressed in all DLBCL-derived cell lines, while isoform 1 is preferentially expressed in cell lines derived from non-germinal center DLBCL. Similarity: Contains 1 PAS (PER-ARNT-SIM) domain. Database links: Entrez Gene: 139135 癌/睾丸抗原63Human SwissProt: Q8IV76 Human Unigene: 160594 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用：癌/睾丸抗原63WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转录调节因子 t-**细胞 b-**细胞 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit