多腺苷二磷酸多聚酶PARP14抗体
规格:1mg/1ml
英文名: PARP14
别名: ADP-ribosyltransferase diphtheria toxin-like 8; ARTD8; B aggressive lymphoma protein 2; BAL2; Collaborator of STAT6; KIAA1268; PAR14_HUMAN; PARP 14; PARP-14; PARP14; pART8; Poly (ADP ribose) polymeras
分子量: 203kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PARP14
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep,
细胞定位:细胞核 细胞浆
多腺苷二磷酸多聚酶PARP14抗体产品介绍:background: Poly(ADP-ribosyl)ation is an immediate DNA damage-dependent posttranslational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. PARP14 belongs to the superfamily of enzymes that perform this modification (Ame et al., 2004 [PubMed 15273990]).[supplied by OMIM, Mar 2008] Function: Enhances STAT6-dependent transcription (By similarity). Has ADP-ribosyltransferase activity. Subunit: Interacts with STAT6. Subcellular Location: 多腺苷二磷酸多聚酶PARP14抗体Nucleus. Cytoplasm. In steady state cells the protein is mostly nuclear. A minor proportion is detected in the cytoplasm. Similarity: Contains 3 Macro domains. Contains 1 PARP catalytic domain. Contains 1 WWE domain. 多腺苷二磷酸多聚酶PARP14抗体Gene ID: 54625 Database links: Entrez Gene: 54625 Human Entrez Gene: 547253 Mouse Entrez Gene: 303903 Rat Omim: 610028 Human SwissProt: Q460N5 Human SwissProt: Q2EMV9 Mouse Unigene: 518203 Human Unigene: 244406 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
多腺苷二磷酸多聚酶PARP14抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid