Rho结合蛋白2抗体
规格:1mg/1ml
英文名: Rhophilin 2
别名: 76 kDa RhoB effector protein; D7Ertd784e; GTP Rho binding protein 2; GTP-Rho-binding protein 2; p76RBE; Rho GTPase binding protein 2; RhoB effector; RhoBP; Rhophilin 2; Rhophilin; Rhophilin like prote
分子量: 77kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Rhophili
交叉反应:Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞浆
Rho结合蛋白2抗体产品介绍:background: This gene encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase binding proteins. The encoded protein binds both GTP- and GDP-bound RhoA and GTP-bound RhoB and may be involved in the organization of the actin cytoskeleton. [provided by RefSeq, Apr 2009] Function: Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity. Subunit: Interacts with GTP-bound RhoA and RhoB. Subcellular Location: Cytoplasm > perinuclear region. Tissue Specificity: Widely expressed. Highly expressed in prostate, trachea,Rho结合蛋白2抗体 stomach, colon, thyroid and pancreas. Expressed at lower level in brain, spinal cord, kidney, placenta and liver. Similarity: Belongs to the RHPN family. Contains 1 BRO1 domain. Contains 1 PDZ (DHR) domain. Contains 1 REM (Hr1) repeat. Gene ID: 85415 Database links: Entrez Gene: 533687 Cow Entrez Gene: 85415 Human Entrez Gene: 52428 Mouse Entrez Gene: 308516 Rat SwissProt: A4FUC9 Cow SwissProt:Rho结合蛋白2抗体 Q8IUC4 Human SwissProt: Q8BWR8 Mouse Unigene: 466435 Human Unigene: 286600 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Rho结合蛋白2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid