磷酸化G蛋白信号转导调节因子16抗体
规格:1mg/1ml
英文名: phospho-RGS16 (Tyr168)
别名: RGS16 (phospho Y168); p-RGS16 (phospho Y168); A28 RGS14; A28 RGS14P; A28-RGS14P; HGNC:9997; hRGS-r; OTTHUMP00000033147; Regulator of G protein signaling 16; Regulator of G protein signalling 16; Regul
分子量: 23kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthesised phosphopeptide derived from human
交叉反应:Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
细胞定位:细胞浆
磷酸化G蛋白信号转导调节因子16抗体产品介绍:background: The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008] Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. May play a role in regulating the kinetics of signaling in the phototransduction cascade. Tissue Specificity: Abundantly expressed in 磷酸化G蛋白信号转导调节因子16抗体retina with lower levels of expression in most other tissues. Post-translational modifications: Palmitoylated on Cys-2 and/or Cys-12. Phosphorylation on Tyr-168 upon EGFR stimulation. Enhanced GTPase accelerating (GAP) activity on G(i)-alpha. Similarity: Contains 1 RGS domain. Gene ID: 6004 Database links: Entrez Gene: 6004 Human Entrez Gene: 19734 Mouse Omim: 602514 Human SwissProt:磷酸化G蛋白信号转导调节因子16抗体 O15492 Human SwissProt: P97428 Mouse Unigene: 413297 Human Unigene: 181709 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化G蛋白信号转导调节因子16抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid