松弛肽2/松弛素2抗体
规格:1mg/1ml
英文名: Relaxin 2
别名: H2; H2-preprorelaxin; H2-RLX; Prorelaxin H2; REL2_HUMAN; Relaxin 2 (H2); Relaxin 2; Relaxin A chain; Relaxin H2; Relaxin, Ovarian, Of Pregnancy; RLN2; RLXH2.
分子量: 21kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Relaxin
交叉反应:Human, Mouse, Rat,
细胞定位:分泌型蛋白
松弛肽2/松弛素2抗体产品介绍:background: Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The protein encoded by this gene is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. [provided by RefSeq, Jan 2013] Function: Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting 松弛肽2/松弛素2抗体growth of pubic ligaments and ripening of the cervix. Subcellular Location: Secreted. Tissue Specificity: Isoform 1 is expressed in the ovary during pregnancy. Also expressed in placenta, decidua and prostate. Isoform 2 is relatively abundant in placenta. It is in much lower abundance in the prostate gland. Not detected in the ovary. Similarity: Belongs to the insulin family. Database links:松弛肽2/松弛素2抗体 Entrez Gene: 6013 Human Entrez Gene: 6019 Human Entrez Gene: 25616 Rat Omim: 179740 Human SwissProt: P04090 Human SwissProt: P04808 Human SwissProt: P47932 Mouse SwissProt: P01347 Rat Unigene: 127032 Human Unigene: 368996 Human Unigene: 5033 Mouse Unigene: 9830 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
松弛肽2/松弛素2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 生长因子和**
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid