SH3结构域结合蛋白D20抗体
规格:1mg/1ml
英文名: SH3D20
别名: ARHGAP27; CAMGAP1; CIN85-associated multi-domain-containing Rho GTPase-activating protein 1; PP905; RHG27_HUMAN; Rho GTPase-activating protein 27; Rho-type GTPase-activating protein 27; SH3 domain con
分子量: 98kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SH3D20
交叉反应:Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞浆 细胞膜
SH3结构域结合蛋白D20抗体产品介绍:background: This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may pay a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2013] Function: Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1. Subcellular Location: Cytoplasm. Membrane. Tissue Specificity: SH3结构域结合蛋白D20抗体Expressed in germinal center B-cell, spleen, chronic lymphocytic leukemia, pancreatic cancer and lung cancer. Similarity: Contains 1 PH domain. Contains 1 Rho-GAP domain. Contains 1 SH3 domain. Contains 3 WW domains. Gene ID: 201176SH3结构域结合蛋白D20抗体 Database links: Entrez Gene: 201176 Human Entrez Gene: 544817 Mouse Entrez Gene: 303583 Rat Omim: 610591 Human SwissProt: Q6ZUM4 Human SwissProt: A2AB59 Mouse SwissProt: Q6TLK4 Rat Unigene: 205326 Human Unigene: 397197 Mouse Unigene: 17895 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
SH3结构域结合蛋白D20抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid