Rab11家族相互作用蛋白2抗体
规格：1mg/1ml
英文名： RAB11-FIP2
别名： RAB11FIP2; KIAA0941; NRip11; RAB11 family interacting protein 2 (class I); Rab11 family-interacting protein 2; RAB11 FIP2 long isoform; Rab11-FIP2; RFIP2; RFIP2_HUMAN.
分子量： 58kD
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RAB11-FI
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, Cat,
细胞定位：细胞膜
Rab11家族相互作用蛋白2抗体产品介绍：Function: A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity. Subcellular Location: Cell membrane. Recycling endosome Rab11家族相互作用蛋白2抗体membrane. Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane. Post-translational modifications: Phosphorylation at Ser-227 by MARK2 regulates epithelial cell polarity. Similarity: Rab11家族相互作用蛋白2抗体Contains 1 C2 domain. Contains 1 FIP-RBD domain. Database links: Entrez Gene: 22841 Human Entrez Gene: 74998 Mouse Entrez Gene: 308003 Rat Omim: 608599 Human SwissProt: Q7L804 Human SwissProt: G3XA57 Mouse Unigene: 173656 Human Unigene: 24167 Mouse Unigene: 64225 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用：Rab11家族相互作用蛋白2抗体WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid